A blog about dermatology and its related topics. Guide to cope up with dermatology disorders and some dermatology treatments.
Fibroblasts are mesenchymal, spindle-shaped cells responsible for the synthesis of the collagen, reticulin, and elastic fibers of the dermis. The initial construction of all three of these fibers occurs within the fibroblast, but posttranslational modification of each of them occurs extracellularly when enzymes clip the terminal portions from the fibrillar molecules. Elastic fibers are branched […]
The smoothness and suppleness of the skin depend largely on the presence of adequate amounts of water in the outer epidermal stratum corneum cells. Water is furnished to the epidermis by plasma that percolates throughout the underlying papillary dermis. This moisture diffuses through the epidermis and is eventually lost to the atmosphere in the form […]
One or more deep, undermined ulcers known as pyoderma gangrenosum may develop on the lower extremities of patients with inflammatory bowel disease and several other types of systemic illness. These ulcers are generally filled with healthy granulation tissue and are surprisingly free of pus and crust. The undermined margin of skin around the ulcer is […]
Antihistamines are primarily used in the treatment of urticaria and for the amelioration of pruritus resulting from various causes. Two major categories of antihistamines are available
-H1 blockers
-H2 blockers.
The approximately 30 H1 antagonists are subdivided into several chemical groups, but there is relatively little clinical difference among them. Familiarity with three or four different H1 antihistamines […]
Alopecia Areata
Alopecia areata consists of sharply localized patches of sudden hair loss unaccompanied by any visible evidence of scalp disease. Usually, the patches are completely devoid of hair, but sometimes a few spared, normal hairs are present. Less often, some “broken off” hairs are scattered throughout the bald areas. These presumably occur because of mild […]
Diagnostic Hallmarks
Distribution- generalized, sclerae involved
Skin is normal in texture on palpation
Clinical Presentation
File earliest stage of jaundice is often hard to recognize because the normal skin color masks the yellow hue. There is not a exact correlation between bilirubin levels and the degree of jaundice. However, bilirubin levels generally need to be above 2.5 mg/100 ml […]