A blog about dermatology and its related topics. Guide to cope up with dermatology disorders and some dermatology treatments.
Recognition of the vesiculobullous diseases is usually not difficult. Specifically, cutaneous lesions containing any number of intact, clear, fluid-filled blisters should be assigned to this group. Problems can arise if, in a blistering process, all the roofs have been broken. In this situation the presence of perfectly round erosions with a thin collarette of scale [...]
Diagnostic Hallmarks Distribution – tips and sides of the digits, palms and soles Clustering of minute, noninflammatory vesicles History of recurrent episodes Clinical Presentation Dyshidrosis consists of minute, noninflammatory vesicles located along the lateral sides and tips of the digits. Individual vesicles are rarely more than 1 mm in diameter, but as the disease increases [...]
Diagnostic Hallmarks Distribution: often starts on the extremities but becomes generalized fairly quickly Tense, tough blisters usually arising from normal skin Individual lesions heal spontaneously while new blisters continue to appear Immunofluorescent studies: IgG and C3 in a linear pattern at the dermal-epidermal junction. Clinical Presentation Patients with pemphigoid characteristically develop the disease after the [...]
Diagnostic Hallmarks Distribution: trunk, palms, soles, lips, and other mucous membranes Tense blisters arising from the center of an erythematous base Presence of some target-type lesions Clinical Presentation Most patients with erythema multiforme do not develop bullous lesions . When blisters do occur, they are present from the onset of the illness and usually are [...]
Diagnostic Hallmarks Distribution – elbows, knees, sacrum, and scapular areas Herpetic-like clustering of vesicles Immunofluorescent biopsy studies: granular deposits of immunoglobulin A (IgA) in the papillary dermis Rapid response to dapsone therapy Clinical Presentation As its name “herpetiform” implies, the very uncommon condition, dermatitis herpetiformis, is characterized by the presence of clustered, small vesicles. The [...]
Diagnostic hallmarks Distribution – perioral, genital, and perigenital skin Tight clustering of small vesicles Recurrent episodes in the same location Clinical Presentation Cutaneous infection with Herpesvirus hominis (HSV 1 and HSV 2) results in the appearance of small vesicles of uniform size and shape. Two clinical patterns are commonly seen, herpes labialis and herpes genitalis. [...]
Diagnostic Hallmarks Distribution: plantar aspect, especially instep, of the foot Associated fungal infection of the toenails and web space Positive potassium hydroxide (KOH) preparation from vesicle roof Clinical Presentation Fungal infections can occur anywhere on the body, but blister formation as a component of fungal infection occurs only on the plantar surfaces of the feet. [...]
Diagnostic Hallmarks Distribution: exposed areas, unilateral or asymmetrical location History of specific trauma Clinical Presentation Traumatic bullae occur as a result of friction, thermal burns, or long-term constant pressure (“coma blisters”). A history of friction or burn is ordinarily apparent, but this history may not be given in cases of child abuse. Likewise, a useful, [...]